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Effectiveness of intrapartum azithromycin to prevent infections in planned vaginal births in low-income and middle-income countries: a post-hoc analysis of data from a multicentre, randomised, double-blind, placebo-controlled trial

Carlo, Waldemar A; Tita, Alan T N; Moore, Janet L; Mazariegos, Manolo et al.
Background In 2023, the Azithromycin Prevention in Labor Use (A-PLUS) trial showed intrapartum azithromycin reduces maternal sepsis or death in women with planned vaginal delivery in low-resource settings, but whether it reduces maternal infection is unknown. We aimed to evaluate the effectiveness of int...
Análisis de Datos, Azitromicina, Efectividad, Parto, Infecciones
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Cost-effectiveness of intrapartum azithromycin to prevent maternal infection, sepsis, or death in low-income and middle-income countries: a modelling analysis of data from a randomised, multicentre, placebo-controlled trial

Patterson, Jackie K; Neuwahl, Simon; Mazariegos, Manolo.
Background Sepsis is one of the leading causes of maternal mortality globally. In 2023, the Azithromycin Prevention in Labor Use (A-PLUS) trial showed intrapartum azithromycin for women planning a vaginal birth reduced the risk of maternal sepsis or death and infection. We aimed to evaluate the cost-effe...
Antibacterianos, Azitromicina, Complicaciones Infecciosas del Embarazo, Sepsis, Mortalidad Materna, Análisis Costo-Beneficio, Parto, Países en Desarrollo
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